, Assessment of influence on endothelial function of beta-adrenoceptor blocking agent of Nebivolol and negative catalyst of angiotensine trans- forming enzyme of Quinapril in the patients with arterial hypertension // BSU bulletin. Medicine and pharmacy. - 2017. №3. . - С. 22-26.

Assessment of influence on endothelial function of beta-adrenoceptor blocking agent of Nebivolol and negative catalyst of angiotensine trans- forming enzyme of Quinapril in the patients with arterial hypertension

UDK: 615.036.8

Vascular endothelium plays an important role in regulating such processes as dilation and constriction of vessels, adhesion of platelets and growth of smooth muscular cells in vessels. This article is devoted to the research of the endothelial function of beta- adrenoceptor blocking agent of Nebivolol and negative catalyst of angiotensine trans- forming enzyme of Quinapril and their influence on the patients with arterial hyperten- sion in randomised open-label study. The assessment of influence of these medicines was based onphysical examination data, measurement of blood pressure, endothelium- dependent vasodilation and endothelium-independent vasodilation under ultrasound in- vestigation of brachial artery. It has been found out that antihypertensive therapy with these medications normalizes defective endothelium-dependent and endothelium- independent functions of resistance vessels.

endothelium; adhesion; trombosis; constriction; vasodilation; relaxing fac- tors; neurohormones.